• Skip to main content
  • Skip to primary sidebar
  • Skip to footer
  • Logo
  • Home
  • About
  • Categories
    • Feature
    • Cardiology trends
    • Cardiology research news
    • Conference coverage
    • Consensus reports & Position papers
    • Videos
  • Contact

Cardiology Update

The latest trends and advancements made in cardiology research.

Arrhythmic risk stratification of post-MI patients with preserved ejection fraction identifies high risk subgroup

July 24, 2019

Reading Time: 1 minute

In patients who have experienced myocardial infarction (MI), a moderately reduced level (≤ 35%) of left-ventricular ejection fraction (LVEF) is indicated as the threshold at which cardiologists should consider an implantable cardioverter-defibrillator (ICD), to reduce the likelihood of sudden cardiac death (SCD). Nonetheless, recent studies have indicated that patients with inducible arrhythmia and LVEF > 35% can also benefit from ICD placement. Thus, as the majority of out-of-hospital SCD patients present with LVEF of ≥40%, many questions surround the criteria for ICD placement based on a revised LVEF threshold and the presence of other risk factors.

In the multicenter, prospective, observational-cohort PRESERVE EF study, researchers investigated outcomes in 575 post-MI patients with LVEF ≥ 40%. They sought to determine whether risk stratification based on the presence of non-invasive risk factors (NIRFs) and inducible arrythmia could identify patients with relatively well-preserved LVEF (i.e. ≥ 40% ), that might benefit from ICD placement.

Of the 575 patients, 41 were considered as being at high risk for a major arrhythmic event (MAE) based on the presence of ≥ 1 NIRF and arrythmia inducible, according to programed ventricular stimulation (PVS); 37 of these patients (90 %) were fitted with an ICD (4 declined). Mean follow-up was 32 months, during which 9 of the 37 ICD devices were activated, indicative of a 22 % prevalence of MAE (equivalent to an annual incidence rate of 8.2%).

The data suggests that in a population of post-MI patients with LVEF ≥ 40 %, ≥ 1 NIRF, and inducible arrythmia, ICD placement could reduce the risk of SCD-related mortality associated with MAEs.

Author: Daniel Guns, Cardiology Update

Original article: Eur Heart J. 2019;0:1-10


Check Out Related Articles

  • Improving survival in patients with advanced heart failure using fully magnetically levitated centrifugal-flow left-ventricular assist devicesImproving survival in patients with advanced heart failure using fully magnetically…
  • Cardiac magnetic resonance imaging used to identify infarct-related arteries in NSTEMI patientsCardiac magnetic resonance imaging used to identify infarct-related arteries in NSTEMI patients
  • Leaving behind left ventricular ejection fraction: heart failure classification using pathophysiological reasoningLeaving behind left ventricular ejection fraction: heart failure classification using…

Primary Sidebar

Cardiology News Highlights

  • Facebook
  • Instagram
  • LinkedIn
  • Twitter

Most featured

Statin therapy: clinical benefits and potential risks

Statin therapies prevent both primary and secondary cardiovascular disease.However, long term safety … Continue Reading about Statin therapy: clinical benefits and potential risks

Renin-angiotensin system inhibitors and TAVR

Renin-angiotensin system inhibitors improve TAVR prognosis

Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure to replace narrowed … Continue Reading about Renin-angiotensin system inhibitors improve TAVR prognosis

AHA 2019 Highlights

AHA 2019: What you need to know

American Heart Association Scientific Sessions, November 16–18, 2019 (Philadelphia, USA) The AHA … Continue Reading about AHA 2019: What you need to know

Browse by topic

Cardiac surgery Electrophysiology General cardiology Heart failure Imaging Interventional cardiology

Footer

Cardiology Update

Providing up-to-date developments in the field of cardiology in a clear and concise manner. All articles are written by professional medical journalists and subsequently reviewed by our editorial board. Cardiology Update provides breaking news, that matter to healthcare professionals in the field of cardiology. Subscribe for free to keep up with cardiology news updated daily.

Recent

  • Renin-angiotensin system inhibitors improve TAVR prognosis
  • AHA 2019: What you need to know
  • Global consensus on CTO-PCI best practices
  • Managing coronary artery disease: MRI vs FFR
  • Prognostic implication of myocardial injury during PCI vs CABG

Search

Browse by topic

Cardiac surgery Electrophysiology General cardiology Heart failure Imaging Interventional cardiology

Terms & Conditions | Privacy | Disclaimer
© Clinicalinx B.V. All rights reserved. Postbus 2278, 1000 CG Amsterdam

We use cookies to provide the services and features offered on our website, and to improve our user experience. Learn more Ok
Privacy & Cookies Policy

Necessary Always Enabled