Better outcomes have been demonstrated with coronary artery bypass grafting (CABG) than with percutaneous coronary intervention (PCI) in three-vessel coronary artery disease (CAD). However, the PCIs performed in these studies were guided by angiography, not fractional flow reserve (FFR) measurements. Investigators aimed to conduct a noninferiority trial to compare FFR-guided … [Read more...] about FAME 3 noninferiority trial: FFR-guided PCI vs CABG
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COAPT Trial: Renal dysfunction and cardiac outcomes in heart failure
Patients with heart failure (HF) and severe secondary mitral regurgitation (MR) frequently also suffer from baseline renal disease (RD). Renal function is further impaired by HF and MR, often accelerating progression to end-stage renal disease (ESRD), necessitating a form of renal replacement therapy (RRT). For patients with MR deemed too high-risk for surgery, the … [Read more...] about COAPT Trial: Renal dysfunction and cardiac outcomes in heart failure
Change in cognitive function in atrial fibrillation patients
Atrial fibrillation (AF) is associated with cognitive decline, even in the absence of clinical stroke. The Swiss AF Cohort (SWISS-AF) study sought to quantify the incidence of silent brain infarcts in patients with AF. Investigators then explored the relationship between silent brain infarcts and cognitive decline. Finally, they also examined if anticoagulation seemed to have … [Read more...] about Change in cognitive function in atrial fibrillation patients
EuroPCR 2022 Highlights
The EuroPCR 2022 Conference occurred from May 17 to 20, 2022, in Paris, France. The EuroPCR 2022 combined onsite and online participation seamlessly. Here is our curated list of some of the top highlights from the EuroPCR 2022 Conference presentations. ARCH trial1: Of the 708 patients (N=2,114) with acute coronary syndrome (ACS), post-percutaneous coronary intervention … [Read more...] about EuroPCR 2022 Highlights
Greater risk of death in heart failure patients hospitalized for COVID-19
The CAPACITY-COVID Collaborative Consortium and LEOSS Study Group examined outcomes of hospitalized COVID-19 patients, both with and without pre-existing heart disease. The CAPACITY-COVID (NCT04325412) registry was launched in March 2020 and has collected data from adults hospitalized for COVID-19 from 74 centres across 13 countries across Europe. The Lean Open Survey on … [Read more...] about Greater risk of death in heart failure patients hospitalized for COVID-19